Considering that the long history cannabis has humanity, many institutions have long suffered. One of these connections is marijuana and “the munchies” — that the greater desire attributed to weed intake.
It is not a totally unfounded association. Many medical marijuana patients cite cannabis’s uncanny ability to induce appetite for a cause of its therapeutic use, however many pot smokers may tell you they do not experience an increased urge to things their pie holes in any way. As it happens, the munchies are actual — sometimes and for many people — science has just started to comprehend why.
What small research enclosing appetite and marijuana appears to point to THC because the cannabinoid accountable for causing appetite as well as the stimulation of the human body’s CB1 receptors, which activates the secretion of hormones which trigger “the munchies,” based on a research printed at the Journal of Biological Chemistry.
The procedure, however, is complex. In another research conducted by Virginia Commonwealth University researchers, CB1 activation also has the opposite effect: curbing appetite.
One medication designed to mimic this effect, promoted under the name Rimonabant, demonstrated effective in curbing appetite. However, in addition, it triggered depression and suicidal ideas , forcing drugmaker Safosi-Aventis to pull Rimonabant in the current market, even after European authorities had originally approved its selling.
A 2011 research printed in the American Journal of Epidemiology found cannabis smokers normally didn’t find a gain in weight as a result of their pot intake. In reality, one of those surveyed, study revealed that the levels of obesity have been greater among non-cannabis users compared to the ones that partake in marijuana. Anecdotally frequent and regular pot smokers report that while smoking weed doesn’t make them hungry, it will enhance the feeling of eating, making food taste and smell better, which raises the general satisfaction of foods.
The intricate mechanisms enclosing the active compounds of the cannabis plant and our bodies are still far from being known enough to control and isolate for certain, desirable effects, as tinkering with marijuana’s appetite effects have demonstrated in the event of Rimonabant.
Since the people’s support for the decriminalization of marijuana increases, scientists and investigators will have more access into this plant and increased chances to comprehend the layered, complex biochemical effects of cannabis and its customers.