It is a painful, sometimes debilitating illness affecting millions of people in america.
However, can cannabis oil supply relief for those who have Crohn’s disease? A new scientific study suggests it could.
“Crohn’s disease is an inflammatory bowel disease (IBD), which is characterized by inflammation and can affect any part of the gastrointestinal (GI) tract, but most commonly the small intestine,” clarified Dr. Timna Naftali, the study’s lead researcher and an expert in gastroenterology in Meir Hospital and Kupat Holim Clinic at Tel Aviv, Israel.
The symptoms include:
- bloody diarrhea
- rectal bleeding
- abdominal pain
“Medications are often prescribed with the aim to control the inflammation. These commonly include antibiotics such as ciprofloxacin, aminosalicylates (a type of anti-inflammatory drug), steroids, immune modifiers, or biologic therapies,” Naftali advised Healthline.
At the very first of its type, randomized, placebo-controlled study, researchers discovered that cannabis generated clinical remission in over fifty percent of individuals after eight weeks of therapy.
Researchers recruited 46 individuals experiencing moderately acute Crohn’s disease for the analysis.
The seriousness of the player’s symptoms and their quality of life has been measured prior to, during, and following treatment.
Gut inflammation has been assessed using an endoscope and by assessing markers of inflammation within blood and feces samples.
Some received a placebo while some others were granted cannabis oil comprising 15 per cent cannabidiol and 4% tetrahydrocannabinol (THC). Both are naturally occurring compounds in cannabis oil.
The study was presented at the United European Gastroenterology seminar held this week.
The analysis has not been printed yet within an peer-reviewed journal.
Naftali confessed the study had a few participants also stated that “moving forward, larger and longer studies are required.”
Following two weeks, researchers said that the participants awarded cannabis oil experienced a substantial improvement in their Crohn’s disease symptoms and quality of life.
Approximately 65 percentage of their cannabis oil team rigorously met the standards for a complete remission of symptoms, while 35 percentage of the placebo group did.
“We have previously demonstrated that cannabis can produce measurable improvements in Crohn’s disease symptoms, but to our surprise, we saw no statistically significant improvements in endoscopic scores or in the inflammatory markers we measured in the cannabis oil group compared with the placebo group,” stated Naftali in a media release.
Naftali explained this finding indicates that it was not the renowned anti-inflammatory impact of cannabis oil which helped relieve symptoms.
“We know that cannabinoids can have profound anti-inflammatory effects, but this study indicates that the improvement in symptoms may not be related to these anti-inflammatory properties,” she explained.
Hemp is really where a lot of the cannabis oil utilized medicinally comes out of.
Although hemp and marijuana come from precisely the exact same plant (Cannabis sativa), they’re not similar.
While marijuana growers have consumed their plants to include elevated levels of THC (the material which gets one “high”), hemp farmers have seldom altered their plants.
Thus cannabis oil will not alter your mental condition, but using it may have other beneficial results.
That is the reason our bodies naturally create cannabis-like compounds (cannabinoids), and we’ve receptors for them known as CB-1 and CB-2 receptors. They are present through the entire human body and mind.
Cannabis oil influences these receptors to reduce both inflammation and pain.
Naftali stated it can help alleviate among Crohn’s inconvenient symptoms.
“Besides increasing appetite, cannabis oil can slow the movement of food through the gut and reduces intestinal secretions, which reduces diarrhea,” she explained.
Crohn’s may have serious complications like malnutrition, bacterial overgrowth, intestinal blockages, and nausea.
“Sixty to 75 percent of Crohn’s patients may require surgery at some stage due to possible complications. The type of procedure will vary depending on the severity and location of the disease in the intestines,” stated Naftali.
Naftali additional that Crohn’s disease is poorly known.
“The exact cause of Crohn’s disease is still unknown,” she clarified. “What is known is that Crohn’s disease is chronic and that it could be the result of an interaction of factors. These include heredity, environmental factors such as bacteria or virus, or an overreaction of the immune system.”The traditional remedies used to relieve Crohn’s symptoms include antibiotics and corticosteroids.
Naftali cautioned that these therapies can include “possible side effects which include susceptibility for infection, allergic response, and rarely, autoimmune disease and even lymphoma (cancer of the lymph system).”
Recent study indicates that cannabis oil has a much better safety profile and no significant side effects in contrast to other medications used to treat this ailment.
Not one of those treatments (like cannabis oil) is a cure.
But, cannabis oil could have the ability to increase quality of lifestyle for some individuals with Crohn’s disease.
Along With also a growing numbers of individuals with Crohn’s are turning into cannabis as a complementary or alternative treatment.
“Patients are using cannabis because it simply makes them feel better,” Naftali said.