Cannabis applications might be connected to high levels of protein related to anxiety, stress

New study points to a potential connection between cannabis use and greater levels of tension and stress, conditions individuals frequently cure exactly with marijuana, in addition to inflammation.

Released in the journal JAMA Psychiatry, the analysis comprising Australian and Canadian scientists discovered that long-term marijuana consumers “showed higher neuroimmune activation or translocator protein levels.”

“Higher levels of this protein were linked with stress and anxiety and also with higher levels of an inflammatory marker in the blood of cannabis users,” the researchers stated.

Additionally, participants in the analysis, that’s the very first of its type, which suffer with “cannabis use disorder,” or a greater dependence of marijuana that may result in dependence, had higher levels of the protein.  

The analysis comprised 24 long-term cannabis users, whose outcomes were contrasted to those of 27 non-cannabis users. Given that the incidence of marijuana use to mitigating symptoms of tension and nervousness, the team anticipated amounts of the mind protein to really go down in cannabis smokers.

But, the writers said these findings do not automatically imply that smoking weed causes stress or anxiety as more study is required.

“It’s important to consider that this study does not suggest a correlation or causation between cannabis use & stress/anxiety, but that there is an association via a specific protein ‘TSPO’,” they composed on Twitter.

The group plans on further investigating the matter by means of a new study that will examine if the protein levels return to normal in people who stopped smoking cannabis. 

“Cannabis is the most commonly used illicit drug in the world but we know very little about the impact it has on the brain, especially in young users whose brains are still developing until the age of 25. These findings are an important step forward, but more studies are needed to better understand the role of cannabinoids and neuroimmune signaling,” Dr. Romina Mizrahi, lead writer and Senior Scientist in the CAMH Research Imaging Centre, stated.

Together with the growing legalization of cannabis, study on its effects is forecast to surge. In the USA, the Drug Enforcement Administration (DEA) recently announced plans to enlarge cannabis study in the nation. 

Skeptics, however, say that the statement may be only for show since the bureau failed to supply a deadline for sorting through applications. The DEA also stated that new regulations approving applications are essential, but gave no hint about what those regulations may entail either. 

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